Umufana wa USB desktop nubwoko bwabafana bato bakoreshwa nicyambu cya USB, bigatuma byoroha gukoreshwa na mudasobwa igendanwa, mudasobwa ya desktop, cyangwa ikindi gikoresho cyose gifite icyambu cya USB. Aba bafana bagenewe kwicara kumeza cyangwa hejuru yubuso kandi bagatanga umuyaga woroshye kugirango ugukonje. Mubisanzwe bafite igishushanyo mbonera kandi gishobora guhindurwa kugirango ikirere gitwarwe mu cyerekezo runaka. Moderi zimwe nazo zitanga igenamigambi ryihuta, kuburyo ushobora kugenzura ubukana bwumwuka. Abakunzi ba USB desktop nigisubizo cyiza kubantu bakorera kumeza umwanya muremure cyangwa bakeneye gukonja ahantu hashyushye, kuko byoroshye gushiraho no gukoresha, kandi ntibisaba isoko yimbaraga zitandukanye.